Fermat’s Last Theorem Proof: What Claude Really Proved in Lean in 11 Days

Fermat's Last Theorem Proof shown as an ancient equation transforming into a glowing digital proof network

Fermat’s Last Theorem was solved decades ago. What changed in 2026 is that the proof can now be checked end to end by a computer. Anthropic says Claude worked largely autonomously for 11 days to produce the first complete machine-checked Fermat’s Last Theorem proof in Lean. The project generated about 13 million lines of Lean, … Read more

mRNA Cancer Vaccine: How Moderna Used AI to Personalize a Treatment That Succeeded in Phase 3

mRNA cancer vaccine concept showing AI-personalized neoantigen targets emerging from a glowing DNA strand

A personalized mRNA cancer vaccine has just crossed a line cancer researchers have been trying to reach for years. On August 19, 2026, Moderna and Merck announced that intismeran autogene, a made-to-order mRNA treatment combined with Keytruda, met key efficacy endpoints in a large Phase 3 melanoma trial. It reduced the risk of cancer returning … Read more

Claude Protein Design: Binders for 14 of 15 Targets, What the 35% Hit Rate Really Means

Claude Protein Design concept image showing an AI-generated protein ribbon structure representing binder discovery

Protein design has spent the last few years becoming dramatically better at generating plausible molecules. Anthropic’s new result asks a different question: can a general-purpose AI agent run the whole campaign, make the design decisions, operate specialist models, and hand scientists a ranked set of proteins that actually bind in the lab? The answer, at … Read more

Is X Biased? A Nature Study Just Ran the Definitive Test

Is X biased feature showing split chronological vs algorithmic feed and a ranking dial

Mini Chart Effect sizes when people switched from chronological to algorithmic (standard deviations) Engagement 0.14 Policy agenda (right) 0.11 Ukraine (pro-Kremlin) 0.12 Trump probes (unfair) 0.08 All policy/news index 0.12 Partisanship 0.00 Affective polarization 0.00 People ask Is X biased the way they ask if the weather is “angry.” It’s a vibe question, born from … Read more